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目的探讨血清降钙素原(PCT)测定在诊断下呼吸道感染中的临床意义。方法回顾性分析2009年3月至2011年10月符合入选标准的83例下呼吸道感染患者的临床资料,其中细菌感染39例,病毒感染24例,支原体感染20例,对其检测的白细胞计数、PCT、C-反应蛋白进行观察。结果细菌感染组PCT(1.20±0.04)ng/ml、病毒感染组(0.15±0.05)ng/ml、支原体感染组(0.16±0.06)ng/ml,三组间比较差异有统计学意义(P<0.05)。结论血清降钙素原血清水平对下呼吸道感染中细菌感染的诊断有着显著的指导意义,特异性高、灵敏度良好、便于检测,可以作为临床上对感染进行鉴别诊断重要依据和指标。
Objective To investigate the clinical significance of serum procalcitonin (PCT) in the diagnosis of lower respiratory tract infection. Methods The clinical data of 83 patients with lower respiratory tract infection who met the inclusion criteria from March 2009 to October 2011 were retrospectively analyzed. Among them, 39 were bacterial infection, 24 were viral infection and 20 were mycoplasma infection. The detection of leukocyte count, PCT, C-reactive protein was observed. Results There were significant differences among the three groups (P <0.01). The infection rates of PCT (1.20 ± 0.04) ng / ml and 0.15 ± 0.05 ng / ml and mycoplasma infection 0.05). Conclusions Serum procalcitonin serum has significant guiding significance for the diagnosis of bacterial infection in lower respiratory tract infection. It has high specificity, good sensitivity and is easy to detect. It can be used as an important basis and index for the differential diagnosis of infection in clinic.