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目的分析卵巢甲状腺乳头状癌(滤泡型)发生远处转移的临床病理特征。方法收集2例卵巢甲状腺乳头状癌(滤泡型)转移至肠道患者的临床病例资料,观察转移灶的病理表现,结合免疫组化染色结果对这种罕见病例进行分析,并复习相关文献。结果患者年龄分别为40岁和48岁,前者于14年前行左卵巢肿瘤切除术,术后多次复发和转移,最后一次转移至肠道;后者于8年前行全子宫及双附件切除术,术后7年转移至肠道,形态学均呈甲状腺乳头状癌(滤泡型)的表现,免疫组化显示TTF1和TG(+)。结论发生于卵巢的甲状腺乳头状癌(滤泡型)罕见,容易复发和远处转移,需要长期随访。
Objective To analyze the clinicopathological features of distant metastasis of papillary thyroid carcinoma (follicular type) in ovary. Methods The clinical data of 2 patients with papillary thyroid carcinoma (follicular type) translocating to the intestinal tract were collected. The pathological findings of the metastases were observed. The rare cases were analyzed by immunohistochemical staining and the related literatures were reviewed. Results The patients were 40 years old and 48 years old respectively. The former underwent left ovarian tumor resection 14 years ago, recurred and transferred many times after operation, and finally transferred to the intestine. The latter performed uterus and double attachment 8 years ago Resection, 7 years after the transfer to the intestine, morphology was papillary thyroid carcinoma (follicular) performance, immunohistochemistry showed TTF1 and TG (+). Conclusions Papillary thyroid carcinoma (follicular type), which occurs in the ovary, is rare and prone to recurrence and distant metastasis and requires long-term follow-up.