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目的:了解2012-2014年武义县疑似预防接种异常反应(AEFI)的发生特征和监测系统运转情况,为今后提高预防接种服务质量提供科学依据。方法:收集所有2012-2014年全国AEFI监测系统内报告的个案数据,并运用描述性统计方法对数据进行分析。结果:2012-2014年共通过全国AEFI监测系统报告个案109例,AEFI报告发生率为18.09/10万,其中一般反应77例,占70.64%;异常反应26例,占23.85%;偶合症6例,占5.5%;一般反应以发热、红肿、硬结为主,占93.51%,异常反应以过敏性皮疹为主,占69.23%;以≤1岁儿童,占76.15%,;95例AEFI在接种后24小时内发生,占87.16%;报告共涉及20种疫苗,无细胞百白破疫苗报告最多,占25.69%;2012-2014年乡级覆盖率分别为27.78%、83.33%、100%,48小时报告率、48小时内调查率、个案完整率均为100%,2012年3日内调查表报告率为85.71%,2013和2014年为100%。结论:武义县AEFI监测系统运作情况正常,但是监测敏感性偏低,今后要加强对接种单位的培训和指导,进一步提高监测敏感性和监测质量。
OBJECTIVE: To understand the occurrence characteristics of AEFI and the operation of surveillance system in Wuyi County from 2012 to 2014 so as to provide a scientific basis for improving the quality of vaccination services in the future. Methods: All case reported data from the national AEFI monitoring system for 2012-2014 were collected and analyzed using descriptive statistics. Results: A total of 109 AEFI surveillance cases were reported from 2012 to 2014 in China. The incidence of AEFI was 18.09 / 100 000, of which 77 were general and 70.64% were normal. Twenty-six were abnormal, accounting for 23.85% , Accounting for 5.5%; general reaction to fever, redness, induration, accounting for 93.51%, abnormal reaction to allergic rash, accounting for 69.23%; children ≤ 1 year, accounting for 76.15%; 95 cases of AEFI after inoculation Accounting for 87.16% of the total. Twenty vaccines were reported in this report, with the highest reported cell-free diphtheria-associated vaccine (25.69%). The coverage rate at township level in 2012-2014 was 27.78%, 83.33%, 100% and 48 hours respectively The report rate, the survey rate within 48 hours and the case complete rate were both 100%. The survey report rate was 85.71% within 3 days of 2012 and 100% between 2013 and 2014. Conclusion: The operation of AEFI monitoring system in Wuyi County is normal, but the sensitivity of monitoring is low. In the future, training and guidance on inoculation units should be strengthened to further improve monitoring sensitivity and monitoring quality.