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purpose To study the outcome of penetrating keratoplasty (PK) in eyws with a glaucoma an-Meier survival analysis,l o-grank test,repeated-measures analysis of variance(ANOVA)-,Fisher exact test,andχ 2 were used in group comparisons.Multivariate an alysis was performed using the Cox proportional hazards model.Results The percentages of clear grafts in the glaucoma drainage de-vice group were 58.5%and 25.8%at 1an d 2years,respectively.At these time points,glaucoma was con-trolled in 74.0%and 63.1%of the eyes,respectively.Both medically controlled glaucoma patients and nonglaucomatous patients had higher graft survival per-centages at comparable time points.The presence of a GDD was an important factor influencing graft survival(Hazard ratio =6.8).Conclusion A GDD implant is an independent risk factor for graft fa ilure.Although these devices are effective in controllin g intraocular pressure(IOP)in the majority of eyes in the presence of PK,corneal graft clarity is often compromised.
purpose To study the outcome of penetrating keratoplasty (PK) in eyws with a glaucoma an-Meier survival analysis, l o-grank test, repeated-measures analysis of variance (ANOVA) -, Fisher exact test, and 2 were used in group comparisons .Multivariate an alysis was performed using the Cox proportional hazards model. Results in percentages of clear grafts in the glaucoma drainage de-vice group were 58.5% and 25.8% at 1 aan d 2years, respectively. These time points, glaucoma was con-trolled in 74.0% and 63.1% of the eyes, respectively.Both medically controlled glaucoma patients and nonglaucomatous patients had higher graft survival per-centages at comparable time points. The presence of a GDD was an important factor influencing graft survival (Hazard ratio = 6.8) .Conclusion A GDD implant is an independent risk factor for graft fa ilure .Although these devices are effective in controllin g intraocular pressure (IOP) in the majority of eyes in the presence of PK, corneal graft clarity is often compromised.