甲硝唑作为抗厌氧菌的首选药物已广泛应用于临床,其毒副作用的报道日益增多。为保证用药安全、合理、有效,临床上常需监测其血药浓度来指导用药。鉴于采用唾液浓度比血清浓度更为简便优越,国内已有测定甲硝唑唾 Metronidazole as an anti-anaerobic drug of choice has been widely used in clinical, the reports of its toxic side effects increased. In order to ensure drug safety, reasonable, effective, often need to monitor the blood concentration in the clinic to guide the medication. In view of the use of saliva concentration is more simple and superior serum concentration, the determination of metronidazole