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肝硬化食管静脉曲张破裂出血是种威胁生命的并发症,死亡率达28~80%。既往应用心得安治疗能降低门脉压力,减少代偿良好的幸存者再次破裂出血的危险性,但有一定的副作用。作者对79例内镜证实食管静脉重度曲张占食管腔1/3以上、无胃肠道出血史的肝硬化患者作前瞻性单盲随机研究,其中30例给以无心脏选择性、能明显降低门脉压力而不影响肾血流量的β阻滞剂萘
Cirrhosis of the esophageal variceal bleeding is a life-threatening complication, the mortality rate of 28 to 80%. Previous application of Andean treatment can reduce portal pressure and reduce the risk of compensated survivors rupture again, but there are some side effects. The author of 79 cases of endoscopic confirmed severe esophageal varices accounted for more than 1/3 of the esophagus, cirrhotic patients without gastrointestinal bleeding history of prospective, single-blind randomized study, of which 30 cases were given no cardiac selectivity, can be significantly Beta-blockers that reduce portal pressure without affecting renal blood flow Naphthalene