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目的了解浙江省台州市2009 2015年肾综合征出血热(HFRS)的发病趋势及鼠类种群密度和携带汉坦病毒情况。方法病例资料来源于中国疾病监测信息系统,捕鼠采用夜夹法,鼠携带病毒检测采用免疫荧光法,鼠血清抗体检测采用酶联免疫吸附试验(ELISA)法。结果 2009 2015年台州市HFRS报告发病数为702例,年均报告发病率为1.68/10万。发病主要分布在天台县、三门县和临海市,占发病总数的70.94%;人群以农民为主,占81.34%,发病率与鼠密度存在显著的相关性(r=0.963,P=0.001);7年间监测点捕获鼠类11种1 425只,总鼠密度为3.91%,鼠平均带病毒率为3.72%,带病毒鼠种为黑线姬鼠50只,褐家鼠3只,其他鼠种未检出。结论台州市HFRS疫情维持在较低的水平,黑线姬鼠是主要的传染源及宿主,疫区仍为黑线姬鼠为主的混合型疫区。加强鼠间疫情监测对本病防控具有重要指导意义。
Objective To understand the incidence trend of HFRS in Taizhou, Zhejiang Province from 2009 to 2015 and the population density and the number of carrying Hantaan virus. Methods The case data were collected from China Disease Surveillance Information System. The mice were caught by night clip method, the mouse virus by immunofluorescence method and the mouse serum antibody by enzyme-linked immunosorbent assay (ELISA). Results The incidence of HFRS in Taizhou from 2009 to 2009 was 702 cases, with an average annual incidence of 1.68 / 100,000. The incidence was mainly distributed in Tiantai County, Sanmen County and Linhai City, accounting for 70.94% of the total. The population was dominated by peasants, accounting for 81.34%. There was a significant correlation between the incidence and rat density (r = 0.963, P = 0.001) ; In the 7 years, 11 425 species of rodents were caught at the monitoring sites, the total rat density was 3.91%, the average virus carrying rate in mice was 3.72%, 50 strains of Apodemus agrarius, 3 rodents and other rats Species not detected. Conclusion The epidemic situation of HFRS in Taizhou is kept at a low level. Apodemus agrarius is the main source of infection and host, and the epidemic area is still a mixed epidemic area dominated by Apodemus agrarius. To strengthen the monitoring of epidemic situation of the rat prevention and control of the disease has an important guiding significance.