造血干细胞移植是治疗恶性血液病最有效的方法,临床上仅局限应用于血液科。但是目前已认识到许多肾脏病与干细胞异常有关,以造血干细胞移植治疗IgA肾病、狼疮性肾炎(LN)和肾细胞癌等肾脏病的研究已在国内外展开。本文简要综述近几年来造血干细胞移植与肾脏病治疗相关的研究进展。 Hematopoietic stem cell transplantation is the most effective method of treatment of hematologic malignancies, and is limited to hematology in clinical practice. However, it has been recognized that many kidney diseases are related to the abnormality of stem cells. Studies on renal diseases such as IgA nephropathy, lupus nephritis (LN) and renal cell carcinoma have been carried out at home and abroad with hematopoietic stem cell transplantation. This article briefly reviews the progress of research on hematopoietic stem cell transplantation and renal disease in recent years.