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62例有泌乳素颗粒的垂体腺瘤在肉眼上和光镜下无特征,在电镜下泌乳素分泌颗粒最粗大,最长径可达1 000 nm,形状不规则,有异位的细胞外分泌。细胞内分泌颗粒的多少不等,但它们不代表血中泌乳素的水平。多分泌颗粒可能是功能不活跃的储存细胞。本组20例还合并有生长激素颗粒。
62 cases of pituitary adenomas with prolactin granules had no characteristics on the naked eye and under the light microscope. Under the electron microscope, the prolactin secretory granules were the thickest and the longest diameter was up to 1 000 nm. The shape was irregular and there was ectopic extracellular secretion. The number of endocrine particles varies from cell to cell, but they do not represent the level of prolactin in the blood. Multiple secretory granules may be inactive storage cells. This group of 20 patients also incorporate growth hormone particles.