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内镜下十二指肠乳头括约肌切开术在西方诊治指南中仍被视为治疗胆总管结石的金标准，但在亚洲，内镜下十二指肠乳头气囊扩张术已被内镜医师普遍应用，并作为治疗胆总管结石的常规方法。近年来，内镜下大气囊乳头扩张（ EPLBD）与内镜下乳头小切开联合大气囊扩张（ ESLBD）也越来越多的用于治疗胆总管结石。单独 EPLBD 与 ESLBD 具有同样的取石效果，但均是不能保留Oddi括约肌功能的方法。定期随访对早期发现和治疗再发性胆总管结石是必要的。“,”Although endoscopic sphincterotomy is still considered as a gold standard treatment for com-mon bile duct stones in western guideline , endoscopic papillary balloon dilation is commonly used by the endoscopists in Asia as the first-line treatment for common bile duct stones.In recent years,endoscopic papil-lary large balloon dialation ( EPLBD) and endoscopic papillary large balloon dilation after sphincterotomy ( ESLBD) are more and more used for the treatment of common bile duct stones .EPLBD alone is as effective as ESLBD with limited endoscopic sphincterotomy,but both are not Oddi sphincter preserved procedures. Regular follow up is necessary for the early detection and management of common bile duct stones recur-rence.