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目的 :探讨甲状腺素及免疫球蛋白对早产儿的影响。方法 :设早产儿组 (n =139)、足月儿组 (n =2 8) ,测定血中甲状腺素及免疫球蛋白水平。结果 :早产儿与足月儿组血中免疫球蛋白比较 ,前者均低于后者 ,有显著性差异 (P <0 .0 5 ) ,且窒息、感染及愈后对免疫球蛋白水平均无影响 (P >0 .0 5 ) ;早产儿血清值均低于足月儿组甲状腺素 (P <0 .0 1) ,而早产儿窒息对T3、T4水平无影响 (P >0 .0 5 ) ;早产儿感染者T3水平低于无感染者(P >0 .0 5 ) ;早产儿T4水平低者 ,转归时间较长 (P <0 .0 5 )。结论 :早产儿尤其是有感染者 ,考虑适当补充甲状腺素及免疫球蛋白 ,有利于早日康复。
Objective: To investigate the effect of thyroxine and immunoglobulin on premature infants. Methods: The preterm infants (n = 139) and full-term infants (n = 28) were enrolled in this study. Blood levels of thyroxine and immunoglobulin were measured. Results: Compared with the latter, the immunoglobulin levels in preterm and full-term infants were significantly lower (P <0.05), and the levels of immunoglobulin in asphyxia, infection and prognosis were all lower (P> 0.05). Serum values of premature infants were lower than that of full-term infants (P <0.01), while asphyxia had no effect on T3 and T4 (P> 0.05) ). The level of T3 in preterm infants was lower than that in non-infected ones (P> 0.05). The level of T4 in infants with low preterm infants was longer (P <0.05). Conclusion: Premature children, especially those with infection, consider appropriate supplementation of thyroxine and immunoglobulin, is conducive to early recovery.