由寄生虫(活寄生虫或纯化的寄生虫抗原)激活补体涉及宿主-寄生虫关系的若干机理。大多数在体外进行的实验发现补体激活对寄生虫是致死性的,但有时对寄生虫血症的发展也是重要的。常路和旁路的补体途径二者均可由寄生虫激活。常路途径几乎总是需要涉及抗体,但旁路途径是直接地被寄生虫释放的产物或存在于寄生虫表皮中的物质所激活。补体的激活特别是通过旁路途径亦可能是细胞粘附于寄生虫的先决条件,然后使寄生虫死亡。 Activation of complement by parasites (living parasites or purified parasitic antigens) involves several mechanisms of host-parasite relationships. Most in vitro experiments have found that complement activation is lethal to parasites but is sometimes important for the development of parasitism. Both regular and bypass complement pathways can be activated by parasites. Often the pathway always involves antibodies, but the bypass pathway is activated either directly by the product released by the parasite or by the substance present in the epidermis of the parasite. Activation of complement, especially through the bypass pathway, may also be a prerequisite for cells to adhere to parasites and then kill the parasites.