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目的:探讨家庭雾化吸入治疗毛细支气管炎的可行性,为临床治疗方式提供参考。方法:选取我院2015年1月至2016年1月在门诊诊断为轻/中度毛细支气管炎的患儿177例,按随机分组设计方案分为家庭组85例和医院组92例。两组患儿均采用压缩空气驱动的射流雾化器雾化吸入布地奈德混悬液及0.5%沙丁胺醇雾化溶液,家庭组由经过培训的家长在家中进行,医院组在医院门诊雾化室进行,两组患儿分别于治疗第3天、第5天及第7天监测其喘息缓解时间、喘鸣音消失时间、咳嗽消失时间、疗程、不良反应及家长满意度。结果:医院组总有效率为92.4%,高于家庭组的81.2%(P<0.05);医院组的喘息缓解时间及喘鸣音消失时间为(3.39±1.28)d、(4.01±1.29)d,家庭组喘息缓解时间及喘鸣音消失时间为(3.71±1.26)d、(4.35±1.37)d,两组比较差异有统计学意义(P<0.05);家长满意度中的方便性、依从性家庭组明显高于医院组(P<0.05),而可操作性、安全性、给药规律性三项指标及总满意度家庭组明显低于医院组(P<0.01)。结论:家庭雾化吸入治疗毛细支气管炎暂不可行,有待进一步观察。
Objective: To explore the feasibility of inhalation therapy for bronchiolitis in family and to provide reference for clinical treatment. Methods: A total of 177 children diagnosed as mild / moderate bronchiolitis in our hospital from January 2015 to January 2016 were selected and randomly divided into family group (85 cases) and hospital group (92 cases). Both groups of children were treated with compressed air-driven jet nebulizer inhalation of budesonide suspension and 0.5% albuterol nebulization solution, family group by trained parents at home, the hospital group in the hospital outpatient nebulizer room The two groups of children were monitored on the 3rd, 5th and 7th day of treatment respectively for the time of wheezing relief, wheezing disappearing time, disappearance of cough, duration of treatment, adverse reactions and parents’ satisfaction. Results: The total effective rate in hospital group was 92.4%, which was higher than that in family group (81.2%, P <0.05). The duration of wheezing and breathlessness in hospital group were (3.39 ± 1.28) d and (4.01 ± 1.29) d (3.71 ± 1.26) days and (4.35 ± 1.37) days in the family group, respectively. The difference between the two groups was statistically significant (P <0.05). The convenience of parents in satisfaction was Sex family group was significantly higher than the hospital group (P <0.05), while the operability, safety, administration regularity three indicators and total satisfaction family group was significantly lower than the hospital group (P <0.01). Conclusion: The family inhalation therapy for bronchiolitis is not feasible, pending further observation.