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２０例肝功能轻度损害的肝癌手术病人与２０例非肝癌手术病人，采用静吸复合全麻，术中静滴维库溴铵，通过ＴＯＦ监测肌松程度，使Ｔ４／Ｔ１维持５－１０％之间，观察比较维库溴铵在两组手术病人中的用药量及恢复时间。结果：两组病人的用药量及恢复时间无显著差异。肝癌组分别为０７６±０１４μｇ／ｋｇ．ｍｉｎ及１９１７±５２０ｍｉｎ，非肝癌组分别为０．７５±０．１１μｇ／ｋｇ．ｍｉｎ及１６．５８±５．２０ｍｉｎ，肝癌手术麻醉并不影响维库溴铵的作用时效。在肝功能轻度损害的肝癌手术麻醉中，可按正常剂量应用维库溴铵。
20 cases of hepatocellular carcinoma patients with mild liver damage and 20 cases of non-hepatocellular carcinoma patients were treated with inhalation combined with general anesthesia, intravenous vecuronium was intravenously administered, and degree of muscle relaxation was monitored by TOF to maintain T4/T1 5-10. Between the %, the use of vecuronium bromide was compared between the two groups of surgical patients and the recovery time. Results: There was no significant difference in the dose and recovery time between the two groups of patients. The liver cancer group was 076±014μg/kg. Min and 1917±520min, non-liver cancer group were 0.75±0.11μg/kg. Min and 16.58±5.20min, surgical anesthesia of liver cancer did not affect the effect of vecuronium. In surgical anaesthesia for liver cancer with mildly impaired liver function, vecuronium bromide can be used at normal doses.