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目的:探讨FT3(游离三碘甲状腺原氨酸)、FT4(血清游离甲状腺素)及sTSH(超敏促甲状腺激素)对伴睡眠障碍甲减症的临床应用价值。方法:选取2012年1月~2016年1月期间在我院收治的60例伴睡眠障碍甲减症患者作为观察组,然后根据其不同表现将这60例患者再分为3组,每组各20例,另选取同期在我院接受体检的健康者50例作为对照组,分别测定不同组入选者的FT3、FT4及sTSH水平。结果:观察组患者的FT3、FT4、水平明显低于对照组,sTSH水平明显高于对照组,P<0.05,差异具有统计学意义。伴睡眠障碍甲减症患者中A组患者的FT3、FT4水平明显高于B、C两组,sTSH水平明显低于B、C两组,P<0.05,差异具有统计学意义;B、C两组患者的FT3、FT4、sTSH水平不存在明显差异,P>0.05,差异无统计学意义。结论:通过测定FT3、FT4及sTSH水平可对伴睡眠障碍甲减症作为有效诊断,并可作为临床治疗效果的评估指标,具有较高的应用价值。
Objective: To investigate the clinical value of FT3 (free triiodothyronine), FT4 (serum free thyroxine) and sTSH (hypersensitivity thyroid stimulating hormone) on hypothyroidism with sleep disorder. Methods: From January 2012 to January 2016, 60 patients with hypopnoea syndrome in our hospital were selected as the observation group, then 60 patients were divided into 3 groups according to their different manifestations, each group Twenty patients were selected as the control group. Fifty healthy subjects who received physical examination in our hospital at the same period were selected as the control group. The levels of FT3, FT4 and sTSH in different groups were determined. Results: The levels of FT3 and FT4 in the observation group were significantly lower than those in the control group, and the levels of sTSH in the observation group were significantly higher than those in the control group (P <0.05). The difference was statistically significant. The levels of FT3 and FT4 in group A with sleep disorders hypothyroidism were significantly higher than those in groups B and C, the levels of sTSH were significantly lower than those in groups B and C (P <0.05), and the differences were statistically significant Group FT3, FT4, sTSH levels did not differ significantly, P> 0.05, the difference was not statistically significant. Conclusion: The hypothyroidism with sleep disorders can be effectively diagnosed by measuring the levels of FT3, FT4 and sTSH, and can be used as an evaluation index of clinical therapeutic effect, which has a high value of application.