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硫酸亚鉄片在国外資料上有两种制法:一是用干燥硫酸亚鉄湿法制粒;一是用結晶直接压片法。国內一般是采用直接压片法。十多年来我們对这两种方法都采用过。直接压片的优点是操作簡单,成本低;缺点是暴露在空气中常易崩碎,沒有湿法制粒的那样安定。本文目的在于解决直接压片的崩碎問題。药典規格的硫酸亚鉄含FeSO_4·7H_2O为99～104%的結晶。一般制法是筛磨成12目以下的顆粒后,加入滑润剂压片。压片时常有裂片及很易磨損圓模的缺点,因而也有采取烘去小部分結晶水后再加入少量飴糖等粘合剂的生产方法,压好的片子再上糖衣。含有結晶水的晶
Sulfate tablets in foreign information on the two system of law: First, dry Saponin wet granulation; one is the direct compression of crystalline method. China is generally using direct compression method. For more than a decade we have used both approaches. Direct compression has the advantage of simple operation and low cost; the disadvantage is that it is easy to crumble when exposed to the air and not stable as wet granulation. The purpose of this paper is to solve the problem of crushing of direct compression. Pharmacopoeia specification Sulfate contains FeSO 4 · 7H 2 O 99 ~ 104% of the crystallization. The general system of law is sieved into the following 12 mesh particles, adding lubricant tableting. Pieces are often lobes and easy to wear round the shortcomings of the mold, so there are also taken to bake a small amount of crystal water and then add a small amount of 饴 sugar and other adhesives production methods, the pressure of the film and then add sugar coating. Crystals containing water of crystallization