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对32例急性心肌梗塞(AMI)患者及30例正常人的血浆纤溶酶原(PLG)活性、组织纤溶酶原激活物(t-PA)活性、纤溶酶原激活物抑制剂(PAI)活性进行了检测。结果显示,AMI组患者t-PA活性显著低于对照组,PAI活性、PLG活性则高于对照组;AMI组死亡者的t-PA活性显著低于存活组;再发AMI患者纤溶活性降低而纤溶抑制活性增强;t-PA活性持久而明显降低,预示AMI患者病情严重,预后不良,并可能是AMI患者再梗塞的危险因素之一。
Plasma plasminogen activator (t-PA) activity, plasminogen activator inhibitor (PAI) activity in 32 patients with acute myocardial infarction (AMI) and 30 healthy controls were measured. ) Activity was tested. The results showed that the activity of t-PA in AMI group was significantly lower than that in control group, the PAI activity and PLG activity were higher than those in control group; the activity of t-PA in AMI group was significantly lower than that in survival group; While the fibrinolytic activity was enhanced. The t-PA activity was persistent and significantly decreased, which indicated that the patients with AMI had serious illness and poor prognosis, which may be one of the risk factors of reinfarction in AMI patients.