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目的研究卡前列素氨丁三醇防治剖宫产手术术中及术后出血的临床效果。方法选择2014年3月至2015年3月具有宫缩乏力高危因素而进行剖宫产的产妇80例,随机分为研究组与对照组,每组40例。研究组患者在胎儿分娩出后采取卡前列素氨丁三醇联合缩宫素进行止血,对照组使用缩宫素进行止血。观察两组患者术中的出血量,产后出血的发生率,产后2、24 h的出血量与不良反应。结果研究组患者术中及产后2、24 h的出血量明显少于对照组(P<0.05);研究组产后出血的发生率为7.50%,对照组为22.50%,研究组明显低于对照组(P<0.05);两组患者不良反应的发生率比较差异未见统计学意义(P>0.05)。结论卡前列素氨丁三醇能够有效防治剖宫产手术术中及术后出血,减少产后出血的发生率,安全性较高,值得临床推广。
Objective To study the clinical effect of carboprost trometamol in the prevention and treatment of intraoperative and postoperative bleeding during cesarean section. Methods Eighty maternal women who underwent cesarean section with high risk of uterine attrition from March 2014 to March 2015 were randomly divided into study group and control group with 40 cases in each group. Patients in the study group were given carprost trometamol and oxytocin to stop bleeding after the fetus was delivered, and the control group used oxytocin to stop bleeding. The amount of bleeding during operation, the incidence of postpartum hemorrhage, the amount of bleeding at 2 and 24 hours postpartum and the adverse reactions were observed. Results The bleeding volume of study group was significantly less than that of control group at 2 and 24 hours after operation (P <0.05). The incidence of postpartum hemorrhage was 7.50% in study group and 22.50% in control group, which was significantly lower in study group than in control group (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion Carprost trometamol can effectively prevent intraoperative and postoperative cesarean section bleeding and reduce the incidence of postpartum hemorrhage, which is safe and worthy of clinical promotion.