本实验连续观察了一肾一夹和二肾一夹大鼠术后1、2、4、6和8周的血浆心房肽和去甲肾上腺素含量。二参数于整个观察期均显著高于正常对照组。血浆心房肽浓度与血压的变化呈良好的正相关(r=0.61,P<0.001;r=0.64,P<0.001)。二肾一夹大鼠于术后第四周,一肾一夹大鼠于术后第六周血浆心房肽水平呈下降趋势。 The experiment continuously observed the plasma concentration of atrial natriuretic peptide and norepinephrine at 1, 2, 4, 6 and 8 weeks after the operation of one kidney one clip and two kidney one clip rats. The two parameters in the observation period were significantly higher than the normal control group. There was a positive correlation between plasma atrial concentration and blood pressure (r = 0.61, P <0.001; r = 0.64, P <0.001). In the second week after operation, the level of plasma atrial natriuretic peptide in the second kidneys and the second kidneys in one kidney and one clip decreased gradually.