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目的:探讨加味厌食散治疗肝郁脾虚型厌食患儿临床疗效。方法:应用中药加味厌食散治疗小儿肝郁脾虚厌食症260例(硫酸锌对照组82例),治疗3个月后,加味厌食散组临床有效率93.6%,治愈率79.3%体重平均增加1.2kg;身高平均增加2.3cm;防治复感儿有效率92.6%。疗效均优于对照组。治疗肝郁脾虚型厌食患儿中98例缺锌者,治疗后加味厌食散组发锌值平均升高60.05ppm,对照组平均增加39.55ppm。经统计学处理,差异显著(P<0.001)。在测试肝郁脾虚型厌食患儿的尿木糖吸收率实验中,治疗组48例,对照组22例,两组治疗后前组高于后组差异显著(P<0.05)。检测患儿的血红蛋白发现治疗后治疗组患儿的血红蛋白明显高于对照,两组差异显著(P<0.001)。结果:加味厌食散能有效地改善肝郁脾虚型厌食患儿的厌食状况,使患儿的身高和体重增加,此外对于提高厌食症患儿的小肠吸收功能及血红蛋白的含量有一定作用。结论:加味厌食散对肝郁脾虚型厌食患儿有较好的临床疗效。
Objective: To investigate the clinical effects of Jiawei AnYesan in treating children with anorexia of stagnation of liver and spleen. Methods: 260 cases of anorexia of liver stagnation and spleen deficiency (82 cases of zinc deficiency and spleen deficiency syndrome) were treated with Modified Anorexia Powder. After 3 months of treatment, the clinical effective rate was 93.6% and the cure rate was 79.3% and the average weight gain was 1.2kg ; Height increased by 2.3cm on average; prevention and treatment of complex children effective rate of 92.6%. Efficacy than the control group. In the treatment of 98 cases of zinc deficiency in children with anorexia of stagnation of liver qi and stagnation of spleen type, the average value of zinc value increased 60.05ppm after treatment and the control group increased 39.55ppm. Statistically, the difference was significant (P <0.001). In the test of urinary xylose uptake in children with anorexia of stagnation of liver-qi and spleen-type, 48 cases in the treatment group and 22 cases in the control group were significantly higher than the latter group after treatment (P <0.05). The detection of hemoglobin in children found that hemoglobin in treatment group was significantly higher than that in control group after treatment, with significant difference between the two groups (P <0.001). Results: Jiaweisanshixiao powder can effectively improve the anorexia in rats with anorexia of stagnation of qi stagnation due to stagnation of liver qi, and increase the height and weight of infants. In addition, it can play an important role in improving intestinal absorption and hemoglobin content in children with anorexia. Conclusion: Modified Anorexia Powder has good clinical effect on children with anorexia of stagnation of liver-qi and spleen deficiency.