论文部分内容阅读
应用OKT单克隆抗体借助间接免疫荧光法测定49例受检者外周血T细胞亚群,结果表明,喉癌组OKT_8~+细胞百分率显著升高,OKT_4~+/OKT_8~+比值显著低于正常组和良性病变组。并且,喉癌患者外周血中T细胞亚群的分布与临床分期有一定关系。提示喉癌患者总的细胞免疫功能处于抑制状态,晚期表现尤为显著。表明测定外周血T细胞亚群,对于了解喉癌患者的免疫状态、监测病情变化和估价预后有一定临床价值。
The peripheral blood T cell subsets in 49 subjects were measured by indirect immunofluorescence with OKT monoclonal antibody. The results showed that the percentage of OKT_8~+ cells in the laryngeal cancer group was significantly higher, and the ratio of OKT_4~+/OKT_8~+ was significantly lower than normal. Group and benign lesions. In addition, the distribution of T lymphocyte subsets in peripheral blood of patients with laryngeal cancer is related to the clinical stage. The overall cellular immune function of patients with laryngeal cancer is inhibited, especially in the late stage. It has been demonstrated that the determination of peripheral blood T cell subsets has certain clinical value for understanding the immune status of laryngeal cancer patients, monitoring the changes of the disease, and evaluating the prognosis.