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目的探讨心酰安(MCA)、1,6二磷酸果糖(FDP)辅助治疗重症毛细支气管炎的疗效。方法对2004年10月至2006年12月期间住院的重症毛细支气管炎的患儿165例,分为A、B两组,A组给予常规的平喘、控制感染、镇静、吸氧及对症支持治疗等;B组在同A组的基础上,加用MCA 3~5 mg/(kg.d)与FDP每次200~250 mg/kg,2次/d,5~7 d。结果B组在喘憋缓解时间、肺部啰音消失时间、住院时间较A组短,差异具有统计学意义(P<0.05)。B组发生并发症5例,而A组18例,差异具有统计学意义(t=8.15,P<0.05)。结论MCA联合FDP辅助治疗重症毛细支气管炎病情恢复快,病程缩短,并可防治心力衰竭等严重并发症的发生。
Objective To investigate the curative effect of adjuvant treatment of severe bronchiolitis with MCF and FDP. Methods A total of 165 children with severe bronchiolitis admitted to hospital from October 2004 to December 2006 were divided into two groups: group A and group B, and group A received routine antiasthmatic, infection control, sedation, oxygen and symptomatic support The patients in group B were treated with MCA 3 ~ 5 mg / (kg · d) and FDP 200 ~ 250 mg / kg, 2 times / d and 5 ~ 7 days on the same group A respectively. Results In group B, the time to relieve asthma, the disappearance of pulmonary rales and hospital stay were shorter than those in group A (P <0.05). There were 5 complications in group B, while 18 in group A, the difference was statistically significant (t = 8.15, P <0.05). Conclusion MCA combined with FDP adjuvant treatment of severe bronchiolitis recovered faster, shorter course of disease, and can prevent the occurrence of serious complications such as heart failure.