自从中南美洲及东南亚地区陆续报道有抗氯喹的恶性疟以后,近几年在我国海南岛及云南省边陲也相继发现了抗氯喹恶性疟。寻找高效、低毒、对抗药性疟疾有效的新药成为当前疟疾防治研究中的迫切任务之一。 我校抗疟药研究组合成的抗疟新药—磷酸羟基喹哌通过前几年的现场验证证明对恶性疟和间日疟的疗效良好,副反应少,并已 Since Central and South America and Southeast Asia have successively reported that chloroquine-resistant falciparum malaria has been found in recent years in Hainan Island, China and Yunnan Province, have also been found to have chloroquine-resistant falciparum malaria. Finding effective, low-toxic and drug-resistant new drugs has become one of the urgent tasks in the current research on malaria control. Our anti-malarial research team formed an anti-malarial drug - Hydroxyquipira phosphate through field validation a few years ago proved effective against falciparum malaria and Plasmodium vivax, less side effects, and