我双下肢患脉管炎多年,经多方中西医治疗,但效果并不明显。为此我很苦恼。因此,每当我下肢疼痛发作时,就用抽烟来解愁。谁知烟抽得越多,脉管炎的症状却越重。请问这是为什么?吉林王金王金读者:血栓闭塞性脉管炎是一种常见的血管病,它好发于下肢远端血管,是一种进行性血管闭塞性炎症,以肢体末端疼痛、缺血和坏死为特征。其主要病理变化是早期血管痉挛、内膜增厚、管腔变窄;中晚期则血栓形成、管腔闭塞、趾端缺血、坏死、脱落。脉管炎多见于20～40岁的青壮年,寒冷地区发病率较高。目前,虽然脉管炎的确切病因尚未完全明了,但大量资料表明,绝大多数脉管炎患者有一个共同特点,即长期大量吸烟,从而提示吸烟与本病密切有关。究其原因,是由于烟草中的烟碱具有促使血管痉挛收缩的作用,不利于 I have both lower extremities with vasculitis for many years, after many Chinese and Western medicine treatment, but the effect is not obvious. I am very distressed for this. Therefore, every time my lower extremity pain occurs, I use smoking to relieve my anxiety. Who knows the more smoked smoke, vasculitis symptoms are heavier. I would like to ask this is why? Wang Jinwang, Jilin Readers: Thromboangiitis obliterans is a common vascular disease, which occurs in the distal lower extremity vessels, is a progressive vascular occlusive inflammation to the distal limb pain, Ischemia and necrosis are characterized. The main pathological changes are early vasospasm, intimal thickening, narrowing of the lumen; late thrombosis, lumen occlusion, toe ischemia, necrosis, loss. Vasculitis more common in young adults aged 20 to 40, the incidence of cold areas higher. At present, although the exact etiology of vasculitis is not yet fully understood, a large body of data indicates that most vasculitis patients have a common characteristic that long-term smoking is large, suggesting that smoking is closely related to this disease. The reason is because nicotine in tobacco has the effect of promoting the contraction of vasospasm, not conducive to