实验结果表明,大白鼠在经受2小时4℃的寒冷刺激后,其肺泡巨噬细胞及外周血中性粒细胞吞噬率、呼吸道溶菌酶含量、支气管肺泡淋巴细胞和肺门淋巴结细胞的空斑形成细胞(PFC)数目均减少;肺泡巨噬细胞和外周血白细胞移行抑制试验之移行指数明显增大.这些改变提示寒冷刺激不仅可以影响呼吸道的免疫功能,同时亦可影响全身性的免疫功能. The experimental results showed that the phagocytic rate of alveolar macrophages and peripheral blood neutrophils, the content of lysozyme in the airways, the plaque formation in bronchoalveolar lavage cells and hilar lymph node cells of rats after being subjected to cold stimulation at 4 ℃ for 2 hours (PFC) decreased, and the migration index of alveolar macrophages and peripheral blood leukocyte migration inhibition test increased obviously.These changes suggested that cold stimulation could not only affect the immune function of the respiratory tract, but also affect the systemic immune function.