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目的 :探讨计算机辅助声学分析在诊断喉癌及评价喉癌术后发声客观声学上的应用价值。方法 :以 18～ 65岁经检查无喉疾病 50例为正常组。以 4 0例喉癌患者为喉癌组 ,手术方式有声带切除术 ,垂直喉部分切除术 ,次全喉切除术和近全喉切除发音管成形术 ,分别于术前及术后 1～ 2个月测试。以各种原因引起的喉返神经麻痹 2 0例为对照组 ,各组均用声图谱分析仪检测。结果 :发i音时喉癌组术前、术后声学参数 ,如频率均值 ,平均微扰、频率微扰商、振幅微扰商、谐噪比、音调微扰系数与正常组差异有显著性 (P <0 0 5) ,喉返神经麻痹组除频率均值与正常组差异有显著性 (P <0 0 5)外 ,余无明显差异。发a音时 ,除喉癌组术前音调微扰系数外 ,余者差异均有显著性 (P <0 0 5)。结论 :喉癌患者发音参数的频率均值、平均微扰、频率微扰商、振幅微扰商、谐噪比及音调微扰系数与正常组差异有显著性 (P <0 0 5)。发声参数是评价喉癌患者发声客观声学的敏感指标。
Objective: To explore the value of computer-aided acoustic analysis in the diagnosis of laryngeal cancer and evaluate the objective acoustics of laryngeal cancer after operation. Methods: Fifty cases without throat disease examined at 18 ~ 65 years old were normal group. Forty 40 patients with laryngeal cancer were treated by laryngeal cancer. Vocal cord resection, vertical partial laryngectomy, subtotal laryngectomy and near-total laryngectomy were performed in the operation group, Month test. A variety of causes of recurrent laryngeal nerve paralysis 20 cases of control group, each group were detected with the sound spectrum analyzer. Results: The acoustic parameters of laryngeal carcinoma before and after laryngeal cancer such as frequency average, average perturbation, frequency perturbation quotient, amplitude perturbation quotient, harmonic noise ratio and pitch perturbation coefficient were significantly different from those in normal group (P <0.05). There was no significant difference between the two groups except the mean frequency of recurrent laryngeal nerve palsy (P <0 05). In addition to the preoperative tone perturbation coefficient of laryngocarcinoma group, the difference was significant (P <0.05). CONCLUSION: The frequency mean, average perturbation, frequency perturbation quotient, amplitude perturbation quotient, harmonic to noise ratio and pitch perturbation coefficient of pronunciation parameters of laryngeal cancer patients are significantly different from those of normal group (P <0.05). The vocalization parameters are the sensitive indicators to evaluate the objective acoustics of laryngeal cancer patients.