癫痫与双向情感障碍(BD)同为反复发作性的慢性脑功能障碍,二者具有相似的临床特征及病理机制,围癫痫发作期的情感表现与BD发作期症状临床鉴别诊断是一个难点。研究表明二者互为共患因素,可能存在潜在的共存机制如遗传学病因,且均对患者的生活质量及社会预后造成负面影响,应重视共患情绪障碍如BD的评估及管理。 Both epilepsy and bipolar disorder (BD) are recurrent episodes of chronic brain dysfunction. Both of them have similar clinical features and pathological mechanisms. It is difficult to differentiate the seizure performance of seizures from that of BD seizures. Studies show that the two are mutual risk factors, and there may be potential coexistence mechanisms such as genetics, all of which have a negative impact on the quality of life and social prognosis of patients. Emphasis should be placed on the assessment and management of comorbid mood disorders such as BD.