念珠菌性食管炎并不少见,其原因之一是器官移植和慢性衰竭患者日益增多,恶性肿瘤病员存活时间延长,而由于免疫功能低下,易受念珠菌等病原微生物侵袭;其次为食管内窥镜的应用提高了本病的诊断水平。易感因素和发病机理:白色念珠菌对正常人无致病性。健康人咽喉部冲洗物念珠菌培养阳性者占30～50%,大便培养阳性者占65～90%。最常见的菌种为白色念珠菌,其次为郎比可热带假丝酵母(C.tropicalis)或克鲁斯假丝酵母(C.krusei)。人体对念珠菌的易感性与机体防御机能的改变、念珠菌的侵袭力及数量有关。许多种恶性病变、内分泌疾病、营养不良和药物均可使机体对念珠菌的易感性增加。复习963例尸检发现,20%的淋巴肉瘤及白血病患 Candida esophagitis is not uncommon, one of the reasons is the growing number of patients with organ transplantation and chronic failure, prolonged survival of patients with malignant tumors, and due to immune dysfunction, susceptible to pathogenic microorganisms such as Candida invasion; followed by the esophageal endoscopy The application of the mirror improves the diagnosis of this disease. Susceptibility Factors and Pathogenesis: Candida albicans is not pathogenic to normal people. Healthy people throat washing Candida culture positive accounted for 30 to 50%, stool culture positive accounted for 65 to 90%. The most common species is Candida albicans, followed by C.tropicalis or C. krusei. Human susceptibility to Candida and the body’s defense function changes, Candida invasiveness and quantity related. Many kinds of malignant diseases, endocrine diseases, malnutrition and drugs can increase the susceptibility of the body to Candida. Review of 963 autopsy found that 20% of lymphosarcoma and leukemia patients