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目的探讨TNM分期中c N0期甲状腺乳头状癌(PTC),两个年龄组别病人的患侧中央区淋巴结转移的差异。方法 cN0期PTC病人56例,根据TNM分期分成年龄<45岁组(29例)和年龄≥45岁组(27例),应用“卡纳琳”标识中央区淋巴结后行患侧预防性中央区淋巴结清扫(pCND),比较两组病人患侧淋巴结阳性率。结果年龄≥45岁组病人患侧清扫淋巴结(6.19±4.28)枚,阳性淋巴结(1.26±1.91)枚,阳性率20.4%;年龄<45岁组病人患侧清扫淋巴结(4.52±3.55)枚,患侧阳性淋巴结(1.14±1.60)枚,阳性率25.2%。两组患侧清扫淋巴结数、患侧阳性淋巴结数和阳性率比较,差异无统计学意义(P>0.05)。结论 cN0期PTC病人TNM分期的两个年龄组别中,患侧淋巴结阳性率无明显差异,病人是否进行患侧中央区淋巴结清扫,应形成一套综合评估体系。
Objective To investigate the difference of lymph node metastasis in cN0 stage thyroid papillary carcinoma (PTC) between two age groups in TNM staging. Methods Fifty-six patients with PTC in stage cN0 were divided into two groups according to TNM stage, including 45 years old (n = 29) and 27 years old (n = 45) Central lymph node dissection (pCND), compared the two groups of patients with ipsilateral lymph node positive rate. Results The positive lymph nodes (6.19 ± 4.28) and positive lymph nodes (1.26 ± 1.91) were positive in patients ≥45 years of age, and the positive rate was 20.4%. The number of dissected lymph nodes (4.52 ± 3.55) in patients younger than 45 years old Side of the positive lymph nodes (1.14 ± 1.60) pieces, the positive rate of 25.2%. There was no significant difference between the two groups in the numbers of lymph nodes, the number of positive lymph nodes and the positive rate (P> 0.05). Conclusions There is no significant difference in the positive rate of ipsilateral lymph node between the two age groups of TNM staging in cN0 PTC patients. Whether patients should carry out lymphadenectasis in the affected area should form a comprehensive evaluation system.