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目的 观察犬肝微波单纯热凝固化后并发症 ,探讨其发生原因与防治 ,为临床治疗不能切除的中晚期肝癌提供借鉴。方法 采用植入式微波治疗机对犬肝行微波内照射 ,作局部组织微波单纯固化后留置。实验犬分为A、B、C 3组 ,A组行全肝每叶双点微波辐射 ,B组行部分肝叶多点微波辐射 ,C组在B组的处理基础上于术后置腹腔引流管及肌注抗生素。结果 A组犬 75%因肝功能衰竭死亡 ,B、C组全部存活。 7d后探查 ,B组犬 75%出现膈下脓肿。结论 在微波辐射量相同的情况下 ,部分肝叶多点微波辐射比全肝每叶双点辐射安全 ;微波治疗后应常规放置腹腔引流管 ,并注射抗生素预防感染。
Objective To observe the complications of microwave coagulation in dog liver after microwave coagulation. To explore the causes and prevention of liver coagulation and to provide reference for clinical treatment of unresectable advanced liver cancer. METHODS: The implanted microwave treatment machine was used to microwave the dog’s liver and indwelled after local tissue microwave curing. Experimental dogs were divided into groups A, B, and C. Group A received two points of microwave radiation per leaf, group B received multiple microwave radiation from some lobes, and group C received abdominal drainage after surgery in group B. Tube and intramuscular injection of antibiotics. Results 75% of dogs in group A died of hepatic failure, and all groups B and C survived. After 7 days exploration, 75% of dogs in group B had subphrenic abscesses. Conclusion In the case of the same amount of microwave radiation, part of the liver lobe microwave radiation is safer than the whole liver two-leaf radiation; after the microwave treatment, the abdominal drainage tube should be routinely placed, and antibiotics should be injected to prevent infection.