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目的:评估新的微小切口白内障手术(MICS)是否较标准同轴晶状体乳化引起较少的内皮损害方法:年龄相关性白内障患者 200 例随机分配接受标准同轴晶状体乳化(SCP)或 MICS 晶状体乳化。术前及术后1a 测量角膜中央及 12 点内皮细胞计数、细胞大小变异系数、六角形细胞百分比以及角膜中央厚度。结果:患者 173 例完成了试验。在 1a 的随访检查中,MICS 组内皮细胞损失为 6.5204%,而 SCP 组为 8.726%(P<0.00005)。两组在细胞大小变异系数、六角形细胞百分比、术后角膜厚度以及在切口部位和角膜中央测得的内皮细胞密度变异方面无显著差异。在硬性白内障患者中,与手术步骤无关,内皮细胞密度损失的增加量较高。结论:比较 SCP 与 MICS,本研究表明后者引起的内皮细胞密度损失明显地较低。
PURPOSE: To assess whether new micro-incision cataract surgery (MICS) causes less endothelial damage than standard coaxial lens emulsification. METHODS: Two hundred age-related cataract patients were randomly assigned to receive standard coaxial lens emulsification (SCP) or MICS phacoemulsification. The corneal center and 12-point endothelial cell counts, coefficient of variation of cell size, percentage of hexagonal cells and central corneal thickness were measured before and after surgery. Results: 173 patients completed the trial. During the follow-up of 1a, the endothelial cell loss in MICS group was 6.5204%, while that in SCP group was 8.726% (P <0.00005). There was no significant difference in the coefficient of variation in cell size, percentage of hexagonal cells, postoperative corneal thickness, and endothelial cell density variability measured at the incision site and corneal center. In patients with rigid cataracts, there is a higher increase in endothelial cell density loss regardless of the surgical procedure. CONCLUSIONS: In comparing SCP with MICS, this study shows that the latter causes significantly lower endothelial cell density loss.