O-glycosylation pattern of the SARS-CoV-2 spike protein reveals an “O-Follow-N” rule

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Dear Editor,rnSevere acute respiratory syndrome coronavirus-2 (SARS-CoV-2),the causative agent of coronavirus disease 2019 (COVID-19),emerged in late 2019 and has since caused a pandemic.Although there have been extensive studies worldwide,our understanding of this newly emerged pathogen is far from sufficient.The pathogenesis of the SARS-CoV-2 infection is not fully understood,although a “two-stage” hypothesis was proposed in our previous study.1
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