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用生物学方法和间接荧光法分别测定了１１６例乙型肝炎患者外周血ＩＬ－２活性和ＩＬ－２Ｒ表达率。结果表明：急性黄疸型肝炎、慢性活动性肝炎、慢性重症肝炎和亚急性重症肝炎患者外周血ＩＬ－２活性和ＩＬ－２Ｒ表达率均低于正常对照组（Ｐ＜０．０１）；慢性活动性肝炎中两指标的下降水平呈正相关（ｒ＝０．６２２３，Ｐ＜０．０１）。提示检测ＩＬ－２Ｒ表达水平可了解乙肝患者机体免疫状态。
The biological and indirect fluorescence methods were used to determine the IL-2 activity and IL-2R expression in peripheral blood of 116 patients with hepatitis B, respectively. The results showed that the expression of IL-2 and IL-2R in peripheral blood of patients with acute jaundice hepatitis, chronic active hepatitis, chronic severe hepatitis and sub-acute severe hepatitis were lower than those in normal control group (P <0.01) There was a positive correlation between the decline of the two indicators in hepatitis (r = 0.6223, P <0.01). Prompt detection of IL-2R expression levels can understand the immune status of hepatitis B patients.