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本文用地高辛0.125mg,氨酰心安12.5mg合并治疗心衰并快速性房颤32例。每位患者先用地高辛0.125mgQD,14天后加用氨酰心安12.5mgQD二药合用14天。用氨酰心安前后测血清地高辛浓度两次,结果氨酰心安对血清地高辛浓度无影响,加用氨酰心安后心室率明显减慢,心率由114±14次/分降为84±12次/分。P<0.01。心功能也进一步改善,81.25％心功能好转。由于地高辛用量小,未发现洋地黄中毒。因此小剂量地高辛与小剂量氨酰心安合用是治疗心衰并快速房颤的良药。
In this paper, digoxin 0.125mg, atenolol 12.5mg combined treatment of heart failure and rapid atrial fibrillation in 32 cases. Each patient first with digoxin 0.125mgQD, after 14 days plus atenolol 12.5mgQD two drugs combined 14 days. Serum digoxin concentration was measured twice before and after treatment with atenolol, the results of atenolol no effect on serum concentration of digoxin, plus atenolol ventricular rate was significantly slower heart rate from 114 ± 14 beats / min down to 84 ± 12 beats / min. P <0.01. Heart function is further improved, 81.25% heart function improved. Due to the small amount of digoxin, did not find digitalis poisoning. Therefore, low-dose digoxin and low-dose atenolol combination is the treatment of heart failure and rapid atrial fibrillation medicine.