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抗肿瘤与抗病毒剂的理论设计,主要是根据对正常宿主细胞与变异细胞(肿瘤或病毒感染细胞)之间的生物化学差异性为依据的。为了研究阿拉伯糖苷的作用,作者选用了 DNA 和 RNA 的合成酶系统。把各种不同的阿拉伯糖苷三磷酸盐加到不同的 DNA 和 RNA 聚合酶中,来考查它对酶活力的影响。
The theoretical design of anti-tumor and anti-viral agents is based primarily on the biochemical differences between normal host cells and variant cells (tumor or virus-infected cells). In order to study the role of arabinoside, the authors selected DNA and RNA synthetase systems. Various different arabinosyl triphosphates were added to different DNA and RNA polymerases to examine their effect on enzyme activity.