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２０例男性病人，平均年龄６０．５±１．５岁，经冠状动脉造影证实为缺血性心肌病。治疗结果：Ｔｒｉｍｅｔａｚｉｄｉｎｅ（ＴＭＺ）组呼吸困难明显减轻，对照组１例减轻（Ｐ＜０．００１），两组心绞痛病人发作次数无显著差异。对照组８例常规药物治疗剂量不能减少并由于病情恶化加入钙拮抗剂、ＡＣＥ抑制剂，ＴＭＺ组明显减少并未加入辅助治疗（Ｐ＜０，０１）。ＳＴ－－Ｔ改变，心律失常发生类型与发生率均无显著差异Ｐ＜０．１。心腔容量（ＣＶ），左室收缩长度（ＥＬＶＳ）与射血分数（ＥＦ）分别相比为Ｐ＜０．０５，Ｐ＝０．１，Ｐ＜０．０５。
20 cases of male patients, the average age of 60.5 ± 1.5 years old, confirmed by coronary angiography as ischemic cardiomyopathy. Treatment results: Trimetazidine (TMZ) group significantly reduced dyspnea, control group, 1 case (P <0.001), two episodes of angina patients had no significant difference in the number of attacks. In the control group, 8 cases of conventional drug treatment dose can not be reduced and due to the deterioration of the condition, calcium antagonist was added, and ACE inhibitor and TMZ group were significantly reduced without adjuvant therapy (P <0,01). ST - T changes, the incidence of arrhythmia and incidence were not significantly different P <0.1. Cardiac volume (CV), left ventricular systolic length (ELVS) and ejection fraction (EF) were P <0.05, P = 0.1, P <0.05, respectively.