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对本院1986年3月~1991年3月期间89例Ⅰ期和Ⅱ期乳腺癌的随访资料进行分析。男1例,女88例,年龄28~78岁,平均54±11岁,51~59岁为高发年龄组,共29例,占32.5%。肿瘤位于左乳42例,右乳47例,部位在外上象限47例(53%),其次为乳晕下16例(18%)。全组按UICC的TNM分期标准,Ⅰ期52例,Ⅱ期37例。Ⅰ、Ⅱ期病例占同时期全部随访病例的82%(89/108)。经典的Halsted乳腺癌根治术(ClassicalHalstedRadicalMastectomy,HRM)50例和改良式乳腺癌根治术(ModifiedRadicalMastectomg,MRM)39例的临床资料比较,二组病例在肿瘤部位、大小、病理类型、临床分期以及术后化疗等情况均相似(P>0.05)。淋巴结转移在HRM组稍高于MRM组,但亦无统计学意义(P>0.05)。仅在年龄分布稍有差异(P<0.01)。MRM组年龄偏大,可能是临床上对年龄偏大者倾向于作改良式根治术以减轻创伤对患者的打击有关。但从二组资料看来具有可比性,全组病例经5~10年随访,除5例死亡与癌症无关外,HRM和MRM的5年生存率分别为88%和85%?
The follow-up data of 89 patients with stage I and stage II breast cancer during the period from March 1986 to March 1991 in this hospital were analyzed. There were 1 male and 88 female patients aged 28-78 years with an average of 54±11 years old, and 51-59 years old had a high-risk age group with 29 cases in total, accounting for 32.5%. Tumors were located in 42 cases of left breast and 47 cases of right breast, with 47 cases (53%) in the upper quadrant, followed by 16 cases (18%) in the areola. According to the UICC TNM staging criteria, 52 patients were in phase I and 37 in phase II. Stage I and II cases accounted for 82% (89/108) of all follow-up cases in the same period. The clinical data of 50 cases of classic Halsted radical mastectomy (HRM) and 39 cases of modified radical mastectomy (MRM) were compared. The tumor location, size, pathological type, clinical stage, and postoperative course of the two groups were compared. The chemotherapy and other conditions were similar (P>0.05). Lymph node metastasis was slightly higher in the HRM group than in the MRM group, but it was also not statistically significant (P>0.05). Only slightly different in age distribution (P <0.01). The age of the MRM group is too large, which may be related to the tendency of clinically older people to undergo an improved radical mastectomy to reduce the impact of trauma on the patient. However, the data from the two groups appear to be comparable. After 5 to 10 years of follow-up, the 5-year survival rates of HRM and MRM were 88% and 85%, respectively.