探讨急性有机磷农药中毒 (AOPP)肾脏损害临床特点 ,提高对AOPP肾损害的认识。对 5 1例合并肾脏损害的AOPP患者进行临床分析。结果 :AOPP中毒程度越重 ,肾脏损害发生率越高 ,其肾脏损害大多数临床表现较轻 ,多以少尿、蛋白尿、血尿为主 ,并可随AOPP病情好转而恢复 ,但发生急性肾功能衰竭 (ARF)后 ,预后较差 ,死亡率高。笔者认为AOPP肾脏损害大多临床表现较轻 ,一旦出现ARF ,则预后差 ,应提高其认识 ,采取综合措施 ,防治肾损害的发生、发展。 To investigate the clinical features of renal damage caused by acute organophosphorus pesticide poisoning (AOPP) and to improve the understanding of renal damage caused by AOPP. Fifty-one AOPP patients with renal impairment were analyzed clinically. Results: The more serious the poisoning of AOPP was, the higher the incidence of renal damage was. Most of the patients with renal damage had mild clinical manifestations. Mostly oliguria, proteinuria and hematuria were predominant, and they recovered with the improvement of AOPP. However, After failure (ARF), the prognosis is poor and the mortality rate is high. I believe that most of AOPP kidney damage clinical manifestations of less, once the ARF, the prognosis is poor, we should raise their awareness and take comprehensive measures to prevent the occurrence and development of renal damage.