论文部分内容阅读
目的:深入了解186例系统性红斑狼疮(SLE)的发病规律及其临床特点,以提高诊疗水平。方法:对186例SLE患者的一般情况、皮肤黏膜表现、实验室检查等项目进行回顾性分析。结果:所有患者的一般情况、临床特点和实验室检查指标与国内外文献报道基本一致,狼疮活动患者发生血红蛋白降低、红细胞沉降率(ESR)升高、肾功能降低、抗双链脱氧核苷酸(抗dsDNA)阳性的比例高于狼疮未活动患者。结论:SLE是一个终身的,会危及生命的疾病,提高对该病的认识,有助于及时合理的治疗,从根本上改善患者的预后,提高生存率。
Objective: To understand the pathogenesis and clinical features of 186 cases of systemic lupus erythematosus (SLE) in order to improve the diagnosis and treatment. Methods: A retrospective analysis of 186 cases of SLE patients in general, skin and mucous membrane performance, laboratory tests and other items were retrospectively analyzed. Results: The general conditions, clinical features and laboratory tests of all patients were basically consistent with those reported in the literature. The incidence of hemoglobin, elevated erythrocyte sedimentation rate (ESR) and renal function were decreased in patients with lupus activity. The anti-double stranded deoxynucleotidyl transferase (Anti-dsDNA) positive than in patients with lupus inactivity. Conclusion: SLE is a life-long disease that will endanger life, improve the understanding of the disease, help to timely and reasonable treatment, fundamentally improve the prognosis of patients and improve the survival rate.