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联合化疗是目前肿瘤化疗中为大家所共同关注的一个课题,它的进展是随着对肿瘤临床发展规律的认识;对药物、药理学的进一步了解;以及细胞动力学,特别是分子水平研究的进步而开展起来的。它首先在血液、淋巴系统肿瘤的治疗上取得了显著的效果。对于实体瘤,系由Li等于50年代末期首先应用以治疗睾丸癌,以后才进一步探索应用于各种实体瘤,并在乳癌获得较好的疗效。但是,迄今为止,由于对各种实体瘤所获得的动力学资料差异很大,临床疗效往往不一致,也还不够理想。
Combined chemotherapy is a topic of common concern for cancer chemotherapy. Its progress is based on the understanding of the clinical development of tumors; further understanding of drugs and pharmacology; and cell dynamics, especially at the molecular level. Progressed and developed. It first achieved remarkable results in the treatment of blood and lymphatic system tumors. For solid tumors, Li was used to treat testicular cancer first in the late 1950s, and later it was further explored for various solid tumors and achieved better results in breast cancer. However, so far, because of the great differences in kinetic data obtained for various solid tumors, the clinical efficacy is often inconsistent and not ideal.