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采用基因重组抗原（ＳＸＰ１）ＥＬＩＳＡ法检测微丝蚴血症者血清抗体，重组抗原检测的血清抗体为ＩｇＧ（主要为ＩｇＧ４），对２１４例班氏微丝蚴血症者血清阳性反应者为２０４例（９５．３％），２０例流行区“正常人”对照均为阴性，７４份非流行区输血者血清假阳性反应１．４％（１／７４），治疗后６个月血清ＳＸＰ１抗体无明显变化，但疗后１２，２４，３６月抗体显著降低。此法敏感性高，特异性强，重复性好，操作简便，每次采６０μｌ血标本，便可进行试验，作为丝防后期现场应用检查残存微丝蚴血症者有实用价值。
Serum antibodies of microfilariae were detected by ELISA with SXP1 ELISA. The serum antibodies detected by recombinant antigens were IgG (mainly IgG4), and serogroups positive for 204 cases of microfilaremia (95.3%) and 20 normal controls were all negative. Serum false positive reaction (1.4%) was found in 74 non-endemic area blood transfusion recipients. Serum SXP1 antibody No significant change, but after 12, 24, 36 months antibody significantly reduced. This method is highly sensitive, specific, reproducible, easy to operate, each time the blood samples taken 60μl, can be tested as a silkworm anti-retrograde field examination of residual microfilaremia have practical value.