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用放射免疫分析法检测了９０例各型白血病及骨髓增生异常综合征中血清乳铁蛋白（ＬＦ）水平及与中性粒细胞的关系，并动态观察了在急、慢性粒细胞白血病转归中ＬＦ的变化。结果发现：ＬＦ与中性粒细胞绝对值呈显著正相关（ｒ＝０．５５１）。急性粒细胞白血病血清ＬＦ显著降低（Ｐ＜０．０１），慢性粒细胞白血病血清ＩＦ显著升高（Ｐ＜０．０１），药物性粒细胞缺乏时ＬＦ显著降低，在骨髓增生异常综合征中ＬＦ无明显变化。
The relationship between serum lactoferrin (LF) levels and neutrophils in 90 leukemia patients and myelodysplastic syndromes was detected by radioimmunoassay and dynamically observed in the prognosis of acute and chronic myeloid leukemia. LF changes. The results showed that there was a significant positive correlation between LF and the absolute value of neutrophils (r=0.551). Serum LF in acute myeloid leukemia was significantly lower (P<0.01), serum IF in chronic myeloid leukemia was significantly higher (P<0.01), and LF was significantly decreased in the presence of drug-induced agranulocytosis, in myelodysplastic syndrome No significant change in LF.