缺血性脑损伤发生机理是研究缺血性脑血管病的重要课题。以往的研究广泛的、大量的强调和重视到在缺血(缺氧、缺糖)后脑组织细胞的能量代谢障碍。自从Harman提出自由基损伤学说以来,并随着这一理论在生物学领域的认识,使人们对缺血性脑损伤这一课题的研究得到新的进展,并走向更深入的层次,即从分子水平进入量子水平。由于近十年来对自由基测定技术的进步,特别是顺磁共振检测技术(ESR)的出现,使自由基在生物医学研究中已成为非常活跃的研究领域。自由基与自由基病理的概念原子核外的电子运动是由其所处的电子层、电子亚层、轨道和自旋状态四个方面所组成。大多数化合物在其电子轨道都是具有成对的电子,其自旋 The pathogenesis of ischemic brain injury is an important topic in the study of ischemic cerebrovascular disease. A wide range of previous studies, a large number of emphasis and attention to the ischemic (hypoxia, lack of sugar) brain cells after energy metabolism disorders. Since Harman put forward the theory of free radical damage, and with the understanding of this theory in the field of biology, people have made new progress in the research on the topic of ischemic brain injury, and to a more in-depth level, Level into the quantum level. Since the advent of free radical measurement technology in the past decade, especially the paramagnetic resonance detection technology (ESR), free radicals have become a very active research field in biomedical research. The Concept of Free Radical and Free Radical Pathology The movement of electrons outside the nucleus consists of the electron layer, the electron sublayer, the orbit and the spin state. Most compounds have pairs of electrons in their electron orbit, which spin