氟美松(地塞米松)具有多种药理作用,临床应用十分广泛。此药短期常规应用不良反应少,现将氟美松少见的不良反应分别概述如下。1 皮肤、肌肉方面1.1 过敏性皮疹 1例因支气管哮喘给予氟美松10mg、氨茶碱0.25g,加入5％GS250ml中静滴,当液体输入过半后,患者出现烦躁、胸闷、心悸,面及颈部皮肤潮红,并出现大块风团样红色丘疹,停药后,上述症状消失。次日仅滴注氟美松又出现前述表现,停药后皮疹等也相继消失。第3天因哮喘持续状态,再次静滴氟美松10mg,全身皮肤又出现大片风团样丘疹,瘙痒剧烈。经停用氟美松,并给予苯海拉明与氢化可的松后,始疹退痒止。1.2 黑棘皮病(AN) 1例自幼患双眼角膜血管翳,大剂量服 Flumethasone (dexamethasone) has a variety of pharmacological effects, a wide range of clinical applications. Short-term routine use of this medicine adverse reactions less, are the rare side effects of dexamethasone are summarized as follows. 1 skin, muscle 1.1 allergic rash 1 case of bronchial asthma due to flumethasone 10mg, aminophylline 0.25g, added 5% GS250ml in intravenous infusion, when the liquid input more than half of patients with irritability, chest tightness, heart palpitations, surface and Neck and skin flushing, and the emergence of large wind-like red papules, withdrawal, the symptoms disappear. The next day only drip dexamethasone appeared in the aforementioned performance, after stopping the rash have also disappeared. The third day due to the persistence of asthma, once again, intravenous dexamethasone 10mg, systemic skin reappearance of large wind-like papules, severe itching. After stopping dexmedetomidine, and given diphenhydramine and hydrocortisone, it started rash and itch only. 1.2 acanthosis nigricans (AN) 1 case of infants with corneal blood vessels from his eyes, high-dose service