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在1991年第二次自身免疫性疾病免疫介入治疗会议上,许多学者的介绍中,主要有三个结论。通过随机与安慰剂或常规疗法的对照研究证实,环孢菌素对严重银屑病、葡萄膜炎、类风湿性关节炎及肾病综合征有效。虽然人们担心其有副作用,特别是肾毒性,但每日剂量低于5mg/kg时,副作用发生率极低。亦未见机会感染。仅可见少数的淋巴瘤病例(<1:1000),但当停用免疫抑制剂时,通常为可逆性。环孢菌素新的适应证有克罗恩氏病、再生障碍性贫血、原发性胆汁性肝硬变、扁平苔
At the Second Immunization Intervention Conference on Autoimmune Diseases in 1991, many scholars introduced three main conclusions. Cyclosporine is effective against severe psoriasis, uveitis, rheumatoid arthritis, and nephrotic syndrome through randomized controlled studies with placebo or conventional therapy. Although people are concerned about their side effects, especially nephrotoxicity, the incidence of side effects is extremely low at daily doses below 5 mg / kg. Also no chance of infection. Only a few cases of lymphoma are visible (<1: 1000), but are often reversible when immunosuppressants are discontinued. Cyclosporine new indications Crohn’s disease, aplastic anemia, primary biliary cirrhosis, lichen planus