论文部分内容阅读
目的 :探讨儿童脑瘫的可能致病因素。方法 :1998年 10月至 11月在浙江省 15个市县 6 6个乡镇 ,进行了 1～ 6岁小儿脑瘫的现况调查暨病例对照调查。调查儿童总人数为 6 2 94 9人 ,确诊脑瘫 92例。根据 1∶ 2配比原则 ,以同村、同居民区 (或邻村、邻居民区 )、同性别、同岁为每 1个病例选择 2名正常儿童 ,进行病例对照研究。结果 :小儿脑瘫发病有统计学意义的危险因素依次为 :新生儿期疾病史 ;母亲过去疾病史 ;低出生体重 ;母亲月经周期不规则、孕期接触有害物质、孕期营养差 ;父亲年龄偏大。围产期保健作为保护因素有显著性意义。结论 :积极预防和消除脑瘫发病的各种致病可疑危险因素 ,可望降低脑瘫的发生率
Objective: To explore the possible causative factors of cerebral palsy in children. Methods: From October to November 1998, 6 children and adolescents in 15 cities and counties in Zhejiang Province were investigated for the status of children with cerebral palsy aged 1 ~ 6 years and case-control study. The total number of children surveyed was 6,294.9, and 92 cases of cerebral palsy were diagnosed. According to the principle of 1: 2 ratio, 2 normal children were selected for each case in the same village, the same residential area (or neighboring villages, neighborhoods), same sex and same age, and a case-control study was conducted. Results: The risk factors of pediatric cerebral palsy were statistic significance: the history of neonatal disease; the history of maternal past disease; the low birth weight; the irregular menstrual cycle of maternal; the contact with harmful substances during pregnancy; the poor nutrition during pregnancy; and the older father. Perinatal care as a protective factor was significant. Conclusion: It is possible to reduce the incidence of cerebral palsy by actively preventing and eliminating all kinds of suspicious risk factors of cerebral palsy