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目的:了解陕西省彬县大骨节病病区成人及学龄儿童硒营养现状，为采取针对性措施提供依据。方法:2018年，依据大骨节病病情将彬县划分为5个病区等级，选择11个有代表性病区村作为调查村，每个调查村划分为东、西、南、北、中5个方位，每个方位选择2户村民，采集成人发样，进行发硒含量测定。在5个病区等级对应的乡镇小学及1个村小学，采集学龄儿童发样，进行发硒含量测定。结果:共采集成人发样85份，发硒含量均值为231.7 μg/kg，总体处于边缘硒缺乏水平（200 ~ 0.05）；共采集儿童发样162份，发硒含量均值为301.3 μg/kg，总体处于中等硒营养水平（250 ~ < 500 μg/kg），不同病区等级儿童发硒含量比较差异有统计学意义（χ n 2 = 13.627，n P < 0.05）。n 结论:彬县虽从整体上摆脱了大骨节病风险，但是部分成人及儿童硒营养水平仍较低，需加强防控，尤其是针对生活在历史病情相对较重的病区村的学龄儿童。“,”Objective:To assess the present situation of selenium nutrition in adults and school-age children in Kaschin-Beck disease area of Binxian, Shaanxi Province, and provide the basis for taking targeted measures.Methods:Binxian was divided into five grades according to the condition of Kaschin-Beck disease, and 11 representative villages were selected as the survey villages in 2018. Each survey village was located in five directions: east, west, south, north, and middle. Two household villagers were selected from each location, and adult hair samples were collected for hair selenium content determination. And school-age children hair samples were collected at the township central primary schools and 1 village primary school corresponding to the five ward levels, and the selenium content was determined.Results:A total of 85 adult hair samples were collected, the average selenium content was 237.1 μg/kg, generally at the marginal selenium deficiency level (200 - 0.05) . A total of 162 children hair samples were collected, the average selenium content was 301.3 μg/kg, generally at the middle selenium nutrition level (250 - < 500 μg/kg), and there was significant difference among different grades of disease areas (χ n 2 = 13.627, n P < 0.05) .n Conclusion:Although Binxian has got rid of the risk of Kaschin-Beck disease as a whole, the selenium nutrition levels of some adults and children are still low, so it is still necessary to strengthen the prevention and control measures, especially for school-age children living in a relatively serious historical disease villages.