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用红藻氨酸（ＫａｉｎｉｃＡｃｉｄ，ＫＡ）１２ｍｇ／ｋｇ给ＳＤ大鼠颈部皮下注射，诱发动物出现癫痫发作，该癫痫发作于８小时内完全缓解。ＫＡ后１周再次给予ＫＡ（此次为阈下剂量５ｍｇ／ｋｇ），检测上述动物对癫痫刺激的敏感性。结果表明，与对照组比较，于４周前开始并连续灌服微生态调节剂实验组动物癫痫敏感性的形成受到明显抑制（Ｐ＜０００１），同时用免疫细胞化学方法观察大鼠脑内海马部位星形胶质细胞的神经胶质原纤维酸性蛋白（ＧｌｉａｌＦｉｂｒｉｌａｒｙａｃｉｄｉｃｐｒｏｔｅｉｎＧＦＡＰ）免疫反应活性的变化，发现ＫＡ后１～７天，实验组与对照组比较，海马部位神经胶质原纤维酸性蛋白免疫反应活性明显受到抑制。结果表明微生态调节剂的抗癫痫敏感性作用可能与抑制胶质细胞过度增生有关。
Subcutaneous injection into the neck of SD rats with Kainic Acid (KA) at 12 mg / kg induces seizures in the animals and the seizures completely resolved within 8 hours. One week after KA, KA was again administered (this time, the subliminal dose was 5 mg / kg) to test the above animals for their sensitivity to epileptic stimulation. The results showed that compared with the control group, the formation of epilepsy sensitivity was significantly inhibited (P <0001) in the experimental group beginning 4 weeks before and continuously fed with the micro-ecological regulator, meanwhile, the immunocytochemistry Glial fibrillary acidic protein (glial fibrillary acidic protein glial fibrillary acidic protein in the hippocampus in the hippocampus changes (glial fibrillary acidic protein glial fibrillary acidic protein activity was found 1 to 7 days after KA, the experimental group compared with the control group, the hippocampal glial fibrillary acidic protein immunization Reactivity was significantly inhibited. The results showed that the antiepileptic sensitivity of microecological regulator may be related to the inhibition of glial cell hyperplasia.