自从建立遗传毒性的Ames试验后,一般认为细菌是这种毒性试验的适宜生物体,作者研究了细菌迁徙(swarming)抑制试验用以检测霉菌毒素、内酯和二羧酸酐的抑制作用,并和细菌平板生长抑制试验进行了比较。迁徒是由于鞭毛活动引起的表面移位,在营养琼脂表面有动力的细菌从接种线蔓延生长形成扩散区,无动力细菌则不形成扩散区,毒物能抑制迁徒。而平板试验中有动力和无动力细菌接种到整个琼脂表面,除了毒物渗透区域细菌生长受抑外,其余部分细菌都能生长。菌株和受试化合物:选用有动力的奇异变 Since the establishment of the genotoxic Ames test, bacteria are generally considered suitable organisms for this toxicity test. The authors studied bacterial swarming inhibition tests to detect the inhibition of mycotoxins, lactones and dicarboxylic anhydrides and Bacterial plate growth inhibition tests were compared. Migration is due to flagellar activity caused by the surface shift in the dynamic agar agar surface of the bacteria spread from the inoculation line to form a proliferation of diffusion zone, no motility bacteria do not form a diffusion zone, poison can inhibit migration. The plate test motivated and non-motivated bacteria inoculated into the entire agar surface, in addition to bacterial growth inhibition of poison penetration area, the rest of the bacteria can grow. Strain and test compounds: the use of dynamic singular changes