论文部分内容阅读
与年龄有关的黄斑变性是65岁以上的白人视力严重丧失的主要原因,虽然有广泛的分类和流行病学的研究,但仍未发现肯定的病因。此病常见于白种人,黄种人罕见。本文报告单卵双生姐妹患与年龄有关的黄斑变性(ARMD),用遗传检测法证实是单卵双生姐妹。因此,考虑遗传因素可能是ARMD发病的重要原发因素。二姐妹均为85岁白种人,视力一直很好,分别于10年前及13年前均在数月内丧失了中央视力。经屈光矫正后,姐姐的视力:右为手动,左为20/400。妹妹的视力:右眼及左眼均为20/400。眼前部检查,可见晶体有中等程度的核硬化,其它未见异常。眼底检查,姐姐右
Age-related macular degeneration is a major cause of severe vision loss in whites over the age of 65, and although a wide range of taxonomic and epidemiological studies have been conducted, no definitive etiology has been found. This disease is common in Caucasians, yellow rare. This article reports single and twin sibling suffering from age-related macular degeneration (ARMD), using genetic testing confirmed that single-egg twin sisters. Therefore, considering the genetic factors may be an important primary factor in the pathogenesis of ARMD. Both sisters were 85-year-old Caucasian and had good eyesight, losing their central vision within a few months 10 years ago and 13 years ago, respectively. After refractive correction, my sister’s eyesight: the right is manual, the left is 20/400. Sister’s eyesight: right eye and left eye are 20/400. The anterior eye examination shows that the crystals have a moderate degree of nuclear sclerosis and the other no abnormalities. Fundus examination, sister right